Tissue Micro-Array

The “Tissue Micro-Array” (TMA) is a medium-throughput technology that allows multiple cores from different donor blocks to be assembled into a single recipient block. This recipient block is then sectioned to generate slides. This enables the analysis of the expression of a given protein simultaneously across a large number of samples (from 90 to 400 cores, depending on core diameter).

The benefits of this technology include:

• Time-saving, as only one donor block is sectioned, producing a single slide per staining,
• Reduced reagent use, since only one slide per staining is processed,
• Improved reproducibility, as all samples are processed simultaneously and uniformly.

We offer custom creation of TMA blocks. For this, we use the TMArrayer from 3DHistech.

This equipment has the advantage of capturing images of donor blocks both before and after coring. It supports several core diameters — 0.6 mm, 1 mm, and 2 mm.

For further information, please contact the RHEM-IRCM platform via the contact form, selecting the RHEM-IRCM service.

Example of a mouse ear core stained with 3 distinct stains