Les frais acquittés à chaque utilisation d'un appareil ou lors de prestations de services ne permettent ni l'achat des équipements ni leur éventuel amortissement. Ainsi, nos équipements sont acquis par le biais de participation des unités et par des subventions publiques que nous obtenons ou que nos utilisateurs nous font bénéficier. C'est pourquoi il est impératif que chaque utilisateur fasse mention de notre contribution dans leurs publications en nous remerciant. Ceci nous permet de monter aux créneaux pour des soutiens financiers.

Voici la phrase type que nous vous conseillons d'écrire dans vos remerciements:

We acknowledge the “Réseau d’Histologie Expérimentale de Montpellier” - RHEM facility supported by SIRIC Montpellier Cancer (Grant INCa_Inserm_DGOS_12553), the european regional development foundation and the occitanian region (FEDER-FSE 2014-2020 Languedoc Roussillon) for processing our animal tissues, histology technics and expertise.

La liste des publications auxquelles le Réseau d'Histologie Expérimentale de Montpellier a contribué est la suivante:

1- Ruiz M, Toupet K, Maumus M, Rozier P, Jorgensen C, Noël D. TGFBI secreted by mesenchymal stromal cells ameliorates osteoarthritis and is detected in extracellular vesicles. Biomaterials. 2020 Jan;226:119544. doi: 10.1016/j.biomaterials.2019.119544. Epub 2019 Oct 11. PMID: 31648137

2- Hamyeh M, Bernex F, Larive RM, Naldi A, Urbach S, Simony-Lafontaine J, Puech C, Bakhache W, Solassol J, Coopman PJ, Hendriks WJAJ, Freiss G. PTPN13 induces cell junction stabilization and inhibits mammary tumor invasiveness. Theranostics. 2020 Jan 1;10(3):1016-1032. doi: 10.7150/thno.38537. eCollection 2020. PMID: 31938048

3- Saksouk N, Hajdari S, Perez Y, Pratlong M, Barrachina C, Graber C, Grégoire D, Zavoriti A, Sarrazin A, Pirot N, Noël JY, Khellaf L, Fabbrizio E, Julien E, Cammas FM. The mouse HP1 proteins are essential for preventing liver tumorigenesis. Oncogene. 2020 Mar;39(13):2676-2691. doi: 10.1038/s41388-020-1177-8. Epub 2020 Feb 4. PMID: 32020053

4- Martinez Q, Clavel J, Esselstyn JA, Achmadi AS, Grohé C, Pirot N, Fabre PH. Convergent evolution of olfactory and thermoregulatory capacities in small amphibious mammals. Proc Natl Acad Sci U S A. 2020 Apr 21;117(16):8958-8965. doi: 10.1073/pnas.1917836117. Epub 2020 Apr 6. PMID: 32253313

5- Clé M. et al. Study of Usutu virus neuropathogenicity in mice and human cellular models". PLOS Neglected Tropical Diseases.

1- Ferreira-Cardoso S, Delsuc F, Hautier L. Evolutionary Tinkering of the Mandibular Canal Linked to Convergent Regression of Teeth in Placental Mammals. Curr Biol. 2019 Feb 4;29(3):468-475.e3. doi: 10.1016/j.cub.2018.12.023. Epub 2019 Jan 17.PMID: 30661801

2- Ashraf Y, Mansouri H, Laurent-Matha V, Alcaraz LB, Roger P, Guiu S, Derocq D, Robin G, Michaud HA, Delpech H, Jarlier M, Pugnière M, Robert B, Puel A, Martin L, Landomiel F, Bourquard T, Achour O, Fruitier-Arnaudin I, Pichard A, Deshayes E, Turtoi A, Poupon A, Simony-Lafontaine J, Boissière-Michot F, Pirot N, Bernex F, Jacot W, du Manoir S, Theillet C, Pouget JP, Navarro-Teulon I, Bonnefoy N, Pèlegrin A, Chardès T, Martineau P, Liaudet-Coopman E. Immunotherapy of triple-negative breast cancer with cathepsin D-targeting antibodies. J Immunother Cancer. 2019 Feb 4;7(1):29. doi: 10.1186/s40425-019-0498-z. PMID: 30717773

3- Gatinois V, Desprat R, Becker F, Pichard L, Bernex F, Corsini C, Pellestor F, Lemaitre JM. Reprogramming of Human Peripheral Blood Mononuclear Cell (PBMC) from a patient suffering of a Werner syndrome resulting in iPSC line (REGUi003-A) maintaining a short telomere length. Stem Cell Res. 2019 Jul 27;39:101515. doi: 10.1016/j.scr.2019.101515. PMID: 31404747

4- Sibon D, Coman T, Rossignol J, Lamarque M, Kosmider O, Bayard E, Fouquet G, Rignault R, Topçu S, Bonneau P, Bernex F, Dussiot M, Deroy K, Laurent L, Callebert J, Launay JM, Georgin-Lavialle S, Courtois G, Maroteaux L, Vaillancourt C, Fontenay M, Hermine O, Côté F. Enhanced Renewal of Erythroid Progenitors in Myelodysplastic Anemia by Peripheral Serotonin. Cell Rep. 2019 Mar 19;26(12):3246-3256.e4. doi: 10.1016/j.celrep.2019.02.071. PMID: 30893598

5- Ghazale H, Ripoll C, Leventoux N, Jacob L, Azar S, Mamaeva D, Glasson Y, Calvo CF, Thomas JL, Meneceur S, Lallemand Y, Rigau V, Perrin FE, Noristani HN, Rocamonde B, Huillard E, Bauchet L, Hugnot JP. RNA Profiling of the Human and Mouse Spinal Cord Stem Cell Niches Reveals an Embryonic-like Regionalization with MSX1+ Roof-Plate-Derived Cells. Stem Cell Reports. 2019 May 14;12(5):1159-1177. doi: 10.1016/j.stemcr.2019.04.001. Epub 2019 Apr 25. PMID: 31031189

6- Lopez-Juarez A, Lahlou H, Ripoll C, Cazals Y, Brezun JM, Wang Q, Edge A, Zine A. Engraftment of Human Stem Cell-Derived Otic Progenitors in the Damaged Cochlea. Mol Ther. 2019 Jun 5;27(6):1101-1113. doi: 10.1016/j.ymthe.2019.03.018. Epub 2019 Apr 2. PMID:31005598

7- Pagano AF, Arc-Chagnaud C, Brioche T, Chopard A, Py G. Muscle Resting and TGF-β Inhibitor Treatment Prevent Fatty Infiltration Following Skeletal Muscle Injury. Cell Physiol Biochem. 2019;53(1):62-75. doi: 10.33594/000000121. PMID: 31184447

8- Bousquet Mur E, Bernardo S, Papon L, Mancini M, Fabbrizio E, Goussard M, Ferrer I, Giry A, Quantin X, Pujol JL, Calvayrac O, Moll HP, Glasson Y, Pirot N, Turtoi A, Cañamero M, Wong KK, Yarden Y, Casanova E, Soria JC, Colinge J, Siebel CW, Mazieres J, Favre G, Paz-Ares L, Maraver A. Notch inhibition overcomes resistance to tyrosine kinase inhibitors in EGFR-driven lung adenocarcinoma. J Clin Invest. 2019 Dec 17. pii: 126896. doi: 10.1172/JCI126896. PMID: 31671073

9- Lutzmann M, Bernex F, da Costa de Jesus C, Hodroj D, Marty C, Plo I, Vainchenker W, Tosolini M, Forichon L, Bret C, Queille S, Marchive C, Hoffmann JS, Méchali M. MCM8- and MCM9 Deficiencies Cause Lifelong Increased Hematopoietic DNA Damage Driving p53-Dependent Myeloid Tumors. Cell Rep. 2019 Sep 10;28(11):2851-2865.e4. doi: 10.1016/j.celrep.2019.07.095. PMID: 31509747

10- Gatinois V, Desprat R, Becker F, Pichard L, Bernex F, Isidor B, Pellestor F, Lemaitre JM. iPSC line derived from a Bloom syndrome patient retains an increased disease-specific sister-chromatid exchange activity. Stem Cell Res. 2019 Dec 31;43:101696. doi: 10.1016/j.scr.2019.101696. PMID: 31918214

11-Thomas F, Giraudeau M, Gouzerh F, Boutry J, Renaud F, Pujol P, Tasiemski A, Bernex F, Maraver A, Bousquet E, Dormont L, Osterkamp J, Roche B, Hamede R, Ujvari B. The evolution of resistance and tolerance as cancer defences. Parasitology. 2019 Nov 15:1-31. doi: 10.1017/S0031182019001501. [Epub ahead of print] No abstract available. PMID: 31727197

12- Debiais-Thibaud M, Simion P, Ventéo S, Muñoz D, Marcellini S, Mazan S, Haitina T. Skeletal Mineralization in Association with Type X Collagen Expression Is an Ancestral Feature for Jawed Vertebrates. Mol Biol Evol. 2019 Oct 1;36(10):2265-2276. doi: 10.1093/molbev/msz145. PMID: 31270539

13- Mrouj K, Singh P, Sobecki M, Dubra G, Al Ghoul E, Aznar A, Prieto S, Vincent C, Pirot N, Bernex F, Bordignon B, Hassen-Khodja C, Pouzolles M, Zimmerman V, Dardalhon V, Villalba M, Krasinska L, Fisher D. Ki-67 supports global gene expression programmes driving tumourigenesis 2019. BioRxiv. doi: https://doi.org/10.1101/712380. HAL Id: hal-02328718

14- Mangé A, Coyaud E, Desmetz C, Laurent E, Béganton B, Coopman P, Raught B, Solassol J. FKBP4 connects mTORC2 and PI3K to activate the PDK1/Akt-dependent cell proliferation signaling in breast cancer. Theranostics 2019; 9(23):7003-7015. doi:10.7150/thno.35561.

15- Kassouf T, Larive RM, Morel A, Urbach S, Bettache N, Marcial Medina MC, Mèrezègue F, Freiss G, Peter M, Boissière-Michot F, Solassol J, Montcourrier P, Coopman P. The Syk Kinase Promotes Mammary Epithelial Integrity and Inhibits Breast Cancer Invasion by Stabilizing the E-Cadherin/Catenin Complex. Cancers (Basel). 2019 Dec 7;11(12). pii: E1974. doi: 10.3390/cancers11121974. PMID: 31817924

16- Rossitto M, Marchive C, Pruvost A, Sellem E, Ghettas A, Badiou S, Sutra T, Poulat F, Philibert P, Boizet-Bonhoure B. Intergenerational effects on mouse sperm quality after in utero exposure to acetaminophen and ibuprofen. FASEB J. 2019 Jan;33(1):339-357. doi: 10.1096/fj.201800488RRR. PMID: 29979629

17- Rossitto M, Ollivier M, Déjardin S, Pruvost A, Brun C, Marchive C, Nguyen AL, Ghettas A, Keime C, de Massy B, Poulat F, Philibert P, Boizet-Bonhoure B. In utero exposure to acetaminophen and ibuprofen leads to intergenerational accelerated reproductive aging in female mice. Commun Biol. 2019 Aug 13;2:310. doi: 10.1038/s42003-019-0552-x. PMID: 31428698

18- Ruiz M, Maumus M, Fonteneau G, Pers YM, Ferreira R, Dagneaux L, Delfour C, Houard X, Berenbaum F, Rannou F, Jorgensen C, Noël D.TGFβi is involved in the chondrogenic differentiation of mesenchymal stem cells and is dysregulated in osteoarthritis. Osteoarthritis Cartilage. 2019 Mar;27(3):493-503. doi: 10.1016/j.joca.2018.11.005. PMID: 30502449

19- Hached K, Goguet P, Charrasse S, Vigneron S, Sacristan MP, Lorca T, Castro A. ENSA and ARPP19 differentially control cell cycle progression and development. J Cell Biol. 2019 Feb 4;218(2):541-558. doi: 10.1083/jcb.201708105. PMID: 30626720

1- Arena G, Cissé MY, Pyrdziak S, Chatre L, Riscal R, Fuentes M, Arnold JJ, Kastner M, Gayte L, Bertrand-Gaday C, Nay K, Angebault-Prouteau C, Murray K, Chabi B, Koechlin-Ramonatxo C, Orsetti B, Vincent C, Casas F, Marine JC, Etienne-Manneville S, Bernex F, Lombès A, Cameron CE, Dubouchaud H, Ricchetti M, Linares LK, Le Cam L. Mitochondrial MDM2 Regulates Respiratory Complex I Activity Independently of p53. Mol Cell. 2018 Feb 15;69(4):594-609.e8. doi: 10.1016/j.molcel.2018.01.023. PMID: 29452639

2- Ruiz L, Gurlo T, Ravier MA, Wojtusciszyn A, Mathieu J, Brown MR, Broca C, Bertrand G, Butler PC, Matveyenko AV, Dalle S, Costes S. Proteasomal degradation of the histone acetyl transferase p300 contributes to beta-cell injury in a diabetes environment. Cell Death Dis. 2018 May 22;9(6):600. doi: 10.1038/s41419-018-0603-0. PMID: 29789539

3- Naranjo-Gomez M, Lambour J, Piechaczyk M, Pelegrin M. Neutrophils are essential for induction of vaccine-like effects by antiviral monoclonal antibody immunotherapies. JCI Insight. 2018 May 3;3(9). pii: 97339. doi: 10.1172/jci.insight.97339. PMID: 29720574

4- Alloing-Séguier L, Marivaux L, Barczi JF, Lihoreau F, Martinand-Mari C. Relationships Between Enamel Prism Decussation and Organization of the Ameloblast Layer in Rodent Incisors. Anat Rec (Hoboken). 2019 Jul;302(7):1195-1209. doi: 10.1002/ar.24000. Epub 2018 Nov 22. PMID: 30365252

5- Despeyroux A, Duret C, Gondeau C, Perez-Gracia E, Chuttoo L, de Boussac H,Briolotti P, Bony C, Noël D, Jorgensen C, Larrey D, Daujat-Chavanieu M, Herrero A. Mesenchymal stem cells seeded on a human amniotic membrane improve liver regeneration and mouse survival after extended hepatectomy. J Tissue Eng Regen Med. 2018 Apr;12(4):1062-1073. doi: 10.1002/term.2607. Epub 2017 Dec 5. PubMed PMID: 29106037.

6- Van Den Brink DM, Cubizolle A, Chatelain G, Davoust N, Girard V, Johansen S, Napoletano F, Dourlen P, Guillou L, Angebault-Prouteau C, Bernoud-Hubac N, Guichardant M, Brabet P, Mollereau B. Physiological and pathological roles of FATP-mediated lipid droplets in Drosophila and mice retina. PLoS Genet. 2018 Sep 10;14(9):e1007627. doi: 10.1371/journal.pgen.1007627. PMID: 30199545 7- Debiais-Thibaud, M. (2019). In Z. Johanson, C. Underwood, & M. Richter (Eds.), Evolution and Development of Fishes (pp. 110-125). The Evolution of Endoskeletal Mineralisation in Chondrichthyan Fish: Development, Cells and Molecules. Cambridge: Cambridge University Press. doi:10.1017/9781316832172.007

8- Chuchana P, Musset-Bonnefont A-L, Mathieu M, Espinoza F, Teigel M, Toupet K, Ripoll C, Djouad F, Noël D, Jorgensen C, Brondello J-M. Secreted α-Klotho maintains cartilage tissue homeostasis by repressing NOS2 and ZIP8-MMP13 catabolic axis. Aging, 2018, 10: 1442-1453. doi: 10.18632/aging.101481. PMID: 29920476

9- Maria ATJ, Toupet K, Maumus M, Rozier P, Vozenin MC, Le Quellec A, Jorgensen C, Noël D, Guilpain P. Fibrosis Development in HOCl-Induced Systemic Sclerosis: A Multistage Process Hampered by Mesenchymal Stem Cells. Front Immunol. 2018 Nov 5;9:2571. doi: 10.3389/fimmu.2018.02571. eCollection 2018. PMID: 30455706

10- Maria ATJ, Rozier P, Fonteneau G, Sutra T, Maumus M, Toupet K, Cristol JP, Jorgensen C, Guilpain P, Noël D. iNOS Activity Is Required for the Therapeutic Effect of Mesenchymal Stem Cells in Experimental Systemic Sclerosis. Front Immunol. 2018 Dec 21;9:3056. doi: 10.3389/fimmu.2018.03056. eCollection 2018. PMID: 30622540

11- Ruiz M, Maumus M, Fonteneau G, Pers Y-M, Ferreira R, Dagneaux L, Delfour C, Houard X, Berenbaum F, Rannou F, Jorgensen C, Noël D. TGFβI is involved in the chondrogenic differentiation of mesenchymal stem cells and is dysregulated in osteoarthritis. Osteoarthritis and Cartilage. 2018 Nov 28. pii: S1063-4584(18)31547-4. doi: 10.1016/j.joca.2018.11.005. PMID: 30502449

12- Diagouraga B, Clement JAJ, Duret L, Kadlec J, de Massy B, Baudat F. PRDM9 Methyltransferase Activity Is Essential for Meiotic DNA Double-Strand Break Formation at Its Binding Sites. Mol Cell. 2018 Mar 1;69(5):853-865.e6. doi: 10.1016/j.molcel.2018.01.033. PMID: 29478809

13- Kumar R, Oliver C, Brun C, Juarez-Martinez AB, Tarabay Y, Kadlec J, de Massy B. Mouse REC114 is essential for meiotic DNA double-strand break formation and forms a complex with MEI4. Life Sci Alliance. 2018 Dec 10;1(6):e201800259. doi: 10.26508/lsa.201800259. PMID: 30569039

14- Ogier C, Colombo PE, Bousquet C, Canterel-Thouennon L, Sicard P, Garambois V, Thomas G, Gaborit N, Jarlier M, Pirot N, Pugnière M, Vie N, Gongora C, Martineau P, Robert B, Pèlegrin A, Chardès T, Larbouret C. Targeting the NRG1/HER3 pathway in tumor cells and cancer-associated fibroblasts with an anti-neuregulin 1 antibody inhibits tumor growth in pre-clinical models of pancreatic cancer. Cancer Lett. 2018 Sep 28;432:227-236. doi: 10.1016/j.canlet.2018.06.023. PMID: 29935372

15- Bayó-Puxan N, Terrasso AP, Creyssels S, Simão D, Begon-Pescia C, Lavigne M, Salinas S, Bernex F, Bosch A, Kalatzis V, Levade T, Cuervo AM, Lory P, Consiglio A, Brito C, Kremer EJ.

Lysosomal and network alterations in human mucopolysaccharidosis type VII iPSC-derived neurons.

Sci Rep. 2018 Nov 9;8(1):16644. doi: 10.1038/s41598-018-34523-3. PMID: 30413728

16- Lambert K, Hokayem M, Thomas C, Fabre O, Cassan C, Bourret A, Bernex F, Lees J, Demion M, Seyer P, Hugon G, Mercier J, Avignon A, Bisbal C. No Additive Effects of Polyphenol Supplementation and Exercise Training on White Adiposity Determinants of High-Fat Diet-Induced Obese Insulin-Resistant Rats. Oxid Med Cell Longev. 2018 Apr 15;2018:7406946. doi: 10.1155/2018/7406946. eCollection 2018. PMID: 29849911

17- Thomas F, Vavre F, Tissot T, Vittecoq M, Giraudeau M, Bernex F, Misse D, Renaud F, Raven N, Beckmann C, Hamede R, Biro PA, Ujvari B. Cancer Is Not (Only) a Senescence Problem.

Trends Cancer. 2018 Mar;4(3):169-172. doi: 10.1016/j.trecan.2018.01.002. Review. PMID: 2950666718.

18- Lambert K, Hokayem M, Thomas C, Fabre O, Cassan C, Bourret A, Bernex F, Feuillet-Coudray C, Notarnicola C, Mercier J, Avignon A, Bisbal C. Combination of nutritional polyphenols supplementation with exercise training counteracts insulin resistance and improves endurance in high-fat diet-induced obese rats. Sci Rep. 2018 Feb 13;8(1):2885. doi: 10.1038/s41598-018-21287-z.

PMID: 29440695

19- Sohier P, Legrand L, Aktary Z, Grill C, Delmas V, Bernex F, Reyes-Gomez E, Larue L, Vergier B. A histopathological classification system of Tyr::NRASQ61K murine melanocytic lesions: A reproducible simplified classification.Pigment Cell Melanoma Res. 2018 May;31(3):423-431. doi: 10.1111/pcmr.12677. Epub 2017 Dec 22. PMID:29224244

20- Varrault A, Eckardt S, Girard B, Le Digarcher A, Sassetti I, Meusnier C, Ripoll C, Badalyan A, Bertaso F, McLaughlin KJ, Journot L, Bouschet T. Mouse Parthenogenetic Embryonic Stem Cells with Biparental-Like Expression of Imprinted Genes Generate Cortical-Like Neurons That Integrate into the Injured Adult Cerebral Cortex. Stem Cells. 2018 Feb;36(2):192-205. doi: 10.1002/stem.2721. Epub 2017 Nov 10. PMID: 29044892

21- Azar S, Leventoux N, Ripoll C, Rigau V, Gozé C, Lorcy F, Bauchet L, Duffau H, Guichet PO, Rothhut B, Hugnot JP. Cellular and molecular characterization of IDH1-mutated diffuse low grade gliomas reveals tumor heterogeneity and absence of EGFR/PDGFRα activation. Glia. 2018 Feb;66(2):239-255. doi: 10.1002/glia.23240. Epub 2017 Oct 13. PMID: 29027701

22- Enault S, Muñoz D, Simion P, Ventéo S, Sire JY, Marcellini S, Debiais-Thibaud M. Evolution of dental tissue mineralization: an analysis of the jawed vertebrate SPARC and SPARC-L families. BMC Evol Biol. 2018 Aug 30;18(1):127. doi: 10.1186/s12862-018-1241-y. PMID: 30165817

23- Pagano AF, Brioche T, Arc-Chagnaud C, Demangel R, Chopard A, Py G. Short-term disuse promotes fatty acid infiltration into skeletal muscle. J Cachexia Sarcopenia Muscle. 2018 Apr;9(2):335-347. doi: 10.1002/jcsm.12259. Epub 2017 Dec 16. PMID: 29248005

6- Lopez-Juarez A, Lahlou H, Ripoll C, Cazals Y, Brezun JM, Wang Q, Edge A, Zine A. Engraftment of Human Stem Cell-Derived Otic Progenitors in the Damaged Cochlea. Mol Ther. 2019 Jun 5;27(6):1101-1113. doi: 10.1016/j.ymthe.2019.03.018. Epub 2019 Apr 2. PMID:31005598

7- Pagano AF, Arc-Chagnaud C, Brioche T, Chopard A, Py G. Muscle Resting and TGF-β Inhibitor Treatment Prevent Fatty Infiltration Following Skeletal Muscle Injury. Cell Physiol Biochem. 2019;53(1):62-75. doi: 10.33594/000000121. PMID: 31184447

8- Bousquet Mur E, Bernardo S, Papon L, Mancini M, Fabbrizio E, Goussard M, Ferrer I, Giry A, Quantin X, Pujol JL, Calvayrac O, Moll HP, Glasson Y, Pirot N, Turtoi A, Cañamero M, Wong KK, Yarden Y, Casanova E, Soria JC, Colinge J, Siebel CW, Mazieres J, Favre G, Paz-Ares L, Maraver A. Notch inhibition overcomes resistance to tyrosine kinase inhibitors in EGFR-driven lung adenocarcinoma. J Clin Invest. 2019 Dec 17. pii: 126896. doi: 10.1172/JCI126896. PMID: 31671073

9- Lutzmann M, Bernex F, da Costa de Jesus C, Hodroj D, Marty C, Plo I, Vainchenker W, Tosolini M, Forichon L, Bret C, Queille S, Marchive C, Hoffmann JS, Méchali M. MCM8- and MCM9 Deficiencies Cause Lifelong Increased Hematopoietic DNA Damage Driving p53-Dependent Myeloid Tumors. Cell Rep. 2019 Sep 10;28(11):2851-2865.e4. doi: 10.1016/j.celrep.2019.07.095. PMID: 31509747

10- Gatinois V, Desprat R, Becker F, Pichard L, Bernex F, Isidor B, Pellestor F, Lemaitre JM. iPSC line derived from a Bloom syndrome patient retains an increased disease-specific sister-chromatid exchange activity. Stem Cell Res. 2019 Dec 31;43:101696. doi: 10.1016/j.scr.2019.101696. PMID: 31918214

11-Thomas F, Giraudeau M, Gouzerh F, Boutry J, Renaud F, Pujol P, Tasiemski A, Bernex F, Maraver A, Bousquet E, Dormont L, Osterkamp J, Roche B, Hamede R, Ujvari B. The evolution of resistance and tolerance as cancer defences. Parasitology. 2019 Nov 15:1-31. doi: 10.1017/S0031182019001501. [Epub ahead of print] No abstract available. PMID: 31727197

12- Debiais-Thibaud M, Simion P, Ventéo S, Muñoz D, Marcellini S, Mazan S, Haitina T. Skeletal Mineralization in Association with Type X Collagen Expression Is an Ancestral Feature for Jawed Vertebrates. Mol Biol Evol. 2019 Oct 1;36(10):2265-2276. doi: 10.1093/molbev/msz145. PMID: 31270539

13- Mrouj K, Singh P, Sobecki M, Dubra G, Al Ghoul E, Aznar A, Prieto S, Vincent C, Pirot N, Bernex F, Bordignon B, Hassen-Khodja C, Pouzolles M, Zimmerman V, Dardalhon V, Villalba M, Krasinska L, Fisher D. Ki-67 supports global gene expression programmes driving tumourigenesis 2019. BioRxiv. doi: https://doi.org/10.1101/712380. HAL Id: hal-02328718

14- Mangé A, Coyaud E, Desmetz C, Laurent E, Béganton B, Coopman P, Raught B, Solassol J. FKBP4 connects mTORC2 and PI3K to activate the PDK1/Akt-dependent cell proliferation signaling in breast cancer. Theranostics 2019; 9(23):7003-7015. doi:10.7150/thno.35561.

15- Kassouf T, Larive RM, Morel A, Urbach S, Bettache N, Marcial Medina MC, Mèrezègue F, Freiss G, Peter M, Boissière-Michot F, Solassol J, Montcourrier P, Coopman P. The Syk Kinase Promotes Mammary Epithelial Integrity and Inhibits Breast Cancer Invasion by Stabilizing the E-Cadherin/Catenin Complex. Cancers (Basel). 2019 Dec 7;11(12). pii: E1974. doi: 10.3390/cancers11121974. PMID: 31817924

16- Rossitto M, Marchive C, Pruvost A, Sellem E, Ghettas A, Badiou S, Sutra T, Poulat F, Philibert P, Boizet-Bonhoure B. Intergenerational effects on mouse sperm quality after in utero exposure to acetaminophen and ibuprofen. FASEB J. 2019 Jan;33(1):339-357. doi: 10.1096/fj.201800488RRR. PMID: 29979629

17- Rossitto M, Ollivier M, Déjardin S, Pruvost A, Brun C, Marchive C, Nguyen AL, Ghettas A, Keime C, de Massy B, Poulat F, Philibert P, Boizet-Bonhoure B. In utero exposure to acetaminophen and ibuprofen leads to intergenerational accelerated reproductive aging in female mice. Commun Biol. 2019 Aug 13;2:310. doi: 10.1038/s42003-019-0552-x. PMID: 31428698

18- Ruiz M, Maumus M, Fonteneau G, Pers YM, Ferreira R, Dagneaux L, Delfour C, Houard X, Berenbaum F, Rannou F, Jorgensen C, Noël D.TGFβi is involved in the chondrogenic differentiation of mesenchymal stem cells and is dysregulated in osteoarthritis. Osteoarthritis Cartilage. 2019 Mar;27(3):493-503. doi: 10.1016/j.joca.2018.11.005. PMID: 30502449

19- Hached K, Goguet P, Charrasse S, Vigneron S, Sacristan MP, Lorca T, Castro A. ENSA and ARPP19 differentially control cell cycle progression and development. J Cell Biol. 2019 Feb 4;218(2):541-558. doi: 10.1083/jcb.201708105. PMID: 30626720

1- Leduc M, Richard J, Costes S, Muller D, Varrault A, Compan V, Mathieu J, Tanti JF, Pagès G, Pouyssegur J, Bertrand G, Dalle S, Ravier MA. ERK1 is dispensable for mouse pancreatic beta cell function but is necessary for glucose-induced full activation of MSK1 and CREB. Diabetologia. 2017 Oct;60(10):1999-2010. doi: 10.1007/s00125-017-4356-6. Epub 2017 Jul 18. PMID: 28721437

2- Cubizolle A, Guillou L, Mollereau B, Hamel CP, Brabet P. Fatty acid transport protein 1 regulates retinoid metabolism and photoreceptor development in mouse retina. PLoS One. 2017 Jul 3;12(7):e0180148. doi: 10.1371/journal.pone.0180148. eCollection 2017. PMID: 28672005

3- Cosenza S, Ruiz M, Toupet K, Jorgensen C, Noël D. Mesenchymal stem cells derived exosomes and microparticles protect cartilage and bone from degradation in osteoarthritis. Sci Rep. 2017 Nov 24;7(1):16214. doi: 10.1038/s41598-017-15376-8. PMID: 29176667

4- Maumus M, Manferdini C, Toupet K, Casteilla L, Gachet M, Jorgensen C, Lisignoli G, Noël D. Thrombospondin-1 partly mediates the cartilage protective effect of adipose-derived mesenchymal stem cells in osteoarthritis. Front Immunol. 2017 Nov 29;8:1638. doi: 10.3389/fimmu.2017.01638. eCollection 2017. PMID: 29238343

5- Imai Y, Baudat F, Taillepierre M, Stanzione M, Toth A, de Massy B. The PRDM9 KRAB domain is required for meiosis and involved in protein interactions. Chromosoma. 2017 Dec;126(6):681-695. doi: 10.1007/s00412-017-0631-z. Epub 2017 May 19. PMID: 28527011

6- Vincent A., Sportouch C., Covinhes A, Barrère C., Gallot L., Delgado-Betancourt V., Lattuca B., Solecki K., Boisguérin P., Piot C., Nargeot J., Barrère-Lemaire S. Cardiac mGluR1 metabotropic receptors in cardioprotection. Cardiovasc Res. 2017 May 1;113(6):644-655. doi: 10.1093/cvr/cvx024. PMID: 28453728

7- Vincent A, Covinhes A, Barrère C, Gallot L, Thoumala S, Piot C, Heurteaux C, Lazdunski M, Nargeot J, Barrère-Lemaire S. Acute and long-term cardioprotective effects of the Traditional Chinese Medicine MLC901 against myocardial ischemia-reperfusion injury in mice. Scientific Reports 2017 Oct 31;7(1):14701. doi: 10.1038/s41598-017-14822-x. PMID: 29089640

8- Arnould S, Rodier G, Matar G, Vincent C, Pirot N, Delorme Y, Berthet C, Buscail Y, Noël JY, Lachambre S, Jarlier M, Bernex F, Delpech H, Vidalain PO, Janin YL, Theillet C, Sardet C.

Checkpoint kinase 1 inhibition sensitises transformed cells to dihydroorotate dehydrogenase inhibition. Oncotarget. 2017 Jul 12;8(56):95206-95222. doi: 10.18632/oncotarget.19199. eCollection 2017 Nov 10. PMID:29221122

9- Campagne C, Reyes-Gomez E, Picco ME, Loiodice S, Salaun P, Ezagal J, Bernex F, Commère PH, Pons S, Esquerre D, Bourneuf E, Estellé J, Maskos U, Lopez-Bergami P, Aubin-Houzelstein G, Panthier JJ, Egidy G.RACK1 cooperates with NRASQ61K to promote melanoma in vivo. Cell Signal. 2017 Aug;36:255-266. doi: 10.1016/j.cellsig.2017.03.015. Epub 2017 Mar 24. PMID:28343944

10- Katarina Bacevic, Robert Noble, Ahmed Soffar, Orchid Wael Ammar, Benjamin Boszonyik, Susana Prieto, Charles Vincent, Michael E. Hochberg, Liliana Krasinska, Daniel Fisher. Spatial competition constrains resistance to targeted cancer therapy. Nat Commun. 2017; 8: 1995. Published online 2017 Dec 8. doi: 10.1038/s41467-017-01516-1. PMCID: PMC5722825

1- Lacroix M.*, Rodier G.*, Kirsh O.*, Houles T., Delpech H., Seyran B., Gayte L., Casas F., Pessemesse L., Berthet C., Bernex F., Brivet M., Boutron A., Le Cam# and Sardet C.# E4F1 controls a transcriptional program essential for pyruvate dehydrogenase activity. Proc Natl Acad Sci U S A. 2010 Dec 7;107(49):21076-81. doi: 10.1073/pnas.1010167107. Epub 2010 Nov 18. Erratum in: Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14716. PMID:21088222

2- Goguet-Rubio P*, Seyran B*, Gayte L, Bernex F, Sutter A, Delpech H, Linares LK, Riscal R, Repond C, Rodier G, Kirsh O, Touhami J, Noel J, Vincent C, Pirot N, Pavlovic G., Herault Y, Sitbon M, Pellerin L, Sardet C, Lacroix M# and Le Cam L#. E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis. Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):11004-9. doi: 10.1073/pnas.1602751113. Epub 2016 Sep 12. PMID: 27621431

3- Riscal R., Schrepfer E., Arena G., Cissé M.Y, Bellvert F., Heuillet M., Rambow F., Bonneil E., Sabourdy F., Vincent C., Ait-Arsa I., Levade T., Thibaut P., Marine JC., Portais JC., Sarry JE., Le Cam L.# and Linares L.K#. Chromatin-bound MDM2 regulates serine metabolism and redox homeostasis independently of p53. Mol Cell. 2016 Jun 16;62(6):890-902. doi: 10.1016/j.molcel.2016.04.033. Epub 2016 Jun 2. PMID: 27264869

4- Morille M, Toupet K, Montero-Menei C N, Jorgensen C, Noël D. PLGA-based microcarriers induce mesenchymal stem cell chondrogenesis and stimulate cartilage repair in osteoarthritis. Biomaterials. 2016 May; 88:60-9. doi: 10.1016/j.biomaterials.2016.02.022. Epub 2016 Feb 18.

PMID: 26945456

5- Maria A, Toupet K, Bony C, Pirot N, Vozenin M-C, Benoit P, Roger P, Batteux F, Le Quellec A, Jorgensen C, Guilpain P, Noël D. Anti-fibrotic, anti-oxydant and immunomodulatory effects of mesenchymal stem cells in HOCl-induced systemic sclerosis. Arthritis Rheumatol. 2016 Apr;68(4):1013-25. doi: 10.1002/art.39477. PMID: 26474311

6- Maria AT, Toupet K, Maumus M, Fonteneau G, Le Quellec A, Jorgensen C, Guilpain P, Noël D. Human adipose mesenchymal stem cells as potent anti-fibrosis therapy for systemic sclerosis. J. J Autoimmun. 2016 Jun;70:31-9. doi: 10.1016/j.jaut.2016.03.013. Epub 2016 Apr 1. PMID: 27052182

7- Domergue S, Bony C, Maumus M, Toupet K, Frouin E, Rigau V, Vozenin M-C, Magalon G, Jorgensen C, Noël D. Comparison between stromal vascular fraction and adipose mesenchymal stem cells in remodeling hypertrophic scars. PLoS One. 2016 May 26;11(5):e0156161. doi: 10.1371/journal.pone.0156161. eCollection 2016. PMID: 27227960.

8- Maumus M, Roussignol G, Toupet K,Penarier G, Bentz I, Teixeira S, Oustric D, Jung M, Lepage O, Steinberg R, Jorgensen C, Noël D. Utility of a mouse model of osteoarthritis to demonstrate cartilage protection by IFN-γ primed equine mesenchymal stem cells. Front Immunol. 2016 Sep 27;7:392. eCollection 2016. PMID: 27729913

9- Grey C, Espeut J, Ametsitsi R, Kumar R, Luksza M, Brun C, Verlhac MH, Suja JA, de Massy B. SKAP, an outer kinetochore protein, is required for mouse germ cell development. Reproduction. 2016 Mar;151(3):239-51. doi: 10.1530/REP-15-0451. Epub 2015 Dec 14. PMID: 26667018

10- Robert T, Nore A, Brun C, Maffre C, Crimi B, Guichard V, Bourbon HM, de Massy B. The TopoVIB-Like protein family is required for meiotic DNA double-strand break formation. Science. 2016 Feb 26;351(6276):943-9. doi: 10.1126/science.aad5309. PMID: 26917764

11- Zussy C, Loustalot F, Junyent F, Gardoni F, Bories C, Valero J, Desarménien MG, Bernex F, Henaff D, Bayo-Puxan N, Chen JW, Lonjon N, de Koninck Y, Malva JO, Bergelson JM, di Luca M, Schiavo G, Salinas S, Kremer EJ. Coxsackievirus Adenovirus Receptor Loss Impairs Adult Neurogenesis, Synapse Content, and Hippocampus Plasticity. J Neurosci. 2016 Sep 14;36(37):9558-71. doi: 10.1523/JNEUROSCI.0132-16.2016. PMID: 27629708

12- Campagne C, Reyes-Gomez E, Loiodice S, Gadin S, Ezagal J, Bernex F, Abitbol M, Louise A, Beermann F, Panthier JJ, Aubin-Houzelstein G, Egidy G. Haplosufficiency of PAX3 for melanoma development in Tyr: NRASQ61K; Cdkn2a-/- mice allows identification and sorting of melanoma cells using a Pax3GFP reporter allele. Melanoma Res. 2016 Feb;26(1):12-20. doi: 10.1097/CMR.0000000000000212. PMID:26587692

13- Guichet PO, Guelfi S, Ripoll C, Teigell M, Sabourin JC, Bauchet L, Rigau V, Rothhut B, Hugnot JP. Asymmetric Distribution of GFAP in Glioma Multipotent Cells. PLoS One. 2016 Mar 8;11(3):e0151274. doi: 10.1371/journal.pone.0151274. eCollection 2016. PMID: 26953813

14- Bonnefois T, Vernerey MS, Rodrigues V, Totté P, Puech C, Ripoll C, Thiaucourt F, Manso-Silván L. Development of fluorescence expression tools to study host-mycoplasma interactions and validation in two distant mycoplasma clades. J Biotechnol. 2016 Oct 20;236:35-44. doi: 10.1016/j.jbiotec.2016.08.006. Epub 2016 Aug 4.PMID: 27497759

1- Luz-Crawford P, Torres MJ, Noël D, Fernandez A, Toupet K, Alcayaga-Miranda F, Tejedor G, Jorgensen C, Illanes SE, Figueroa FE, Djouad F, Khoury M. The Immunosuppressive Signature of Menstrual Blood Mesenchymal Stem Cells Entails Opposite Effects on Experimental Arthritis and Graft Versus Host Diseases. Stem Cells. 2016 Feb;34(2):456-69. doi: 10.1002/stem.2244. Epub 2015 Dec 3. PMID: 26528946

2- Arsic N, Gadea G, Lagerqvist EL, Busson M, Cahuzac N, Brock C, Hollande F, Gire V, Pannequin J, Roux P. The p53 isoform Δ133p53β promotes cancer stem cell potential. Stem Cell Reports. 2015 Apr 14;4(4):531-40. doi: 10.1016/j.stemcr.2015.02.001. Epub 2015 Mar 5. PMID: 25754205

3- Vera J, Lartigue L, Vigneron S, Gadea G, Gire V, Del Rio M, Soubeyran I, Chibon F, Lorca T, Castro A. Greatwall promotes cell transformation by hyperactivating AKT in human malignancies. Elife. 2015 Nov 27;4. pii: e10115. doi: 10.7554/eLife.10115. PMID: 26613407

4- Colombo PE, du Manoir S, Orsett B, Bras-Gonçalves R, Lambros MB, MacKay A, Nguyen TT, Boissière F, Pourquier D, Bibeau F, Reis-Filho JS, Theillet. Boissière F, Pourquier D, Bibeau F, Reis-Filho JS, Theillet C.Ovarian carcinoma patient derived xenografts reproduce their tumor of origin and preserve an oligoclonal structure. Oncotarget. 2015 Sep 29;6(29):28327-40. doi: 10.18632/oncotarget.5069. PMID: 26334103

5- Ducasse H, Ujvari B, Solary E, Vittecoq M, Arnal A, Bernex F, Pirot N, Misse D, Bonhomme F, Renaud F, Thomas F, Roche B. Can Peto's paradox be used as the null hypothesis to identify the role of evolution in natural resistance to cancer? A critical review. BMC Cancer. 2015 Oct 24;15:792. doi: 10.1186/s12885-015-1782-z. Review. PMID:26499116

6- Tîlmaciu CM, Mathieu M, Lavigne JP, Toupet K, Guerrero G, Ponche A, Amalric J, Noël D, Mutin PH. In vitro and in vivo characterization of antibacterial activity and biocompatibility: a study on silver-containing phosphonate monolayers on titanium. Acta Biomater. 2015 Mar;15:266-77. doi: 10.1016/j.actbio.2014.12.020. Epub 2015 Jan 3. PMID: 25562573

7- Toupet K, Maumus M, Luz-Crawford P, Lombardo E, Lopez-Belmonte J, van Lent P, Garin MI, van den Berg W, Dalemans W, Jorgensen C, Noël D. Survival and biodistribution of xenogenic adipose mesenchymal stem cells is not affected by the degree of inflammation in arthritis. PLoS One. 2015 Jan 5;10(1):e0114962. doi: 10.1371/journal.pone.0114962. eCollection 2015. Erratum in: PLoS One. 2015;10(3):e0120406. PMID: 25559623

8- Deleyrolle L, Sabourin JC, Rothhut B, Fujita H, Guichet PO, Teigell M, Ripoll C, Chauvet N, Perrin F, Mamaeva D, Noda T, Mori K, Yoshihara Y, Hugnot JP. OCAM regulates embryonic spinal cord stem cell proliferation by modulating ErbB2 receptor. PLoS One. 2015 Apr 13;10(4):e0122337. doi: 10.1371/journal.pone.0122337. eCollection 2015. PMID: 25875008

9- Pagano AF, Demangel R, Brioche T, Jublanc E, Bertrand-Gaday C, Candau R, Dechesne CA, Dani C, Bonnieu A, Py G, Chopard A. Muscle Regeneration with Intermuscular Adipose Tissue (IMAT) Accumulation Is Modulated by Mechanical Constraints. PLoS One. 2015 Dec 2;10(12):e0144230. doi: 10.1371/journal.pone.0144230. eCollection 2015. PMID: 26629696

10- AMPK/HuR-Driven IL-20 Post-Transcriptional Regulation in Psoriatic Skin. Garcin G, Guiraud I, Lacroix M, Genthon C, Rialle S, Joujoux JM, Meunier L, Lavabre-Bertrand T, Stoebner PE, Le Gallic L. J Invest Dermatol. 2015 Nov;135(11):2732-2741. doi: 10.1038/jid.2015.282. Epub 2015 Jun 15. PMID: 26176762

11- Bowerman M, Salsac C, Coque E, Eiselt É, Deschaumes RG, Brodovitch A, Burkly LC, Scamps F, Raoul C. Tweak regulates astrogliosis, microgliosis and skeletal muscle atrophy in a mouse model of amyotrophic lateral sclerosis. Hum Mol Genet. 2015 Jun 15;24(12):3440-56. doi: 10.1093/hmg/ddv094. Epub 2015 Mar 12. PMID: 25765661.

1- Philipot D, Guérit D, Platano D, Chuchana P, Olivotto E, Espinoza F, Dorandeu A, Pers YM, Piette J, Borzi RM, Jorgensen C, Noel D, Brondello. p16INK4a and its regulator miR-24 link senescence and chondrocyte terminal differentiation-associated matrix remodeling in osteoarthritis. JM.Arthritis Res Ther. 2014 Feb 27;16(1):R58. doi: 10.1186/ar4494.

2- Rahmoun M, Perez J, Saunders PA, Boizet-Bonhoure B, Wilhelm D, Poulat F, Veyrunes F. Anatomical and molecular analyses of XY ovaries from the African pygmy mouse Mus minutoides. Sex Dev. 2014;8(6):356-63.

3- Lapierre M, Bonnet S, Bascoul-Mollevi C, Ait-Arsa I, Jalaguier S, Del Rio M, Plateroti M, Roepman P, Ychou M, Pannequin J, Hollande F, Parker M, Cavailles V. RIP140 increases APC expression and controls intestinal homeostasis and tumorigenesis. J Clin Invest. 2014 May;124(5):1899-913.

4- Leconet W, Larbouret C, Chardès T, Thomas G, Neiveyans M, Busson M, Jarlier M, Radosevic-Robin N, Pugnière M, Bernex F, Penault-Llorca F, Pasquet JM, Pèlegrin A, Robert B. Preclinical validation of AXL receptor as a target for antibody-based pancreatic cancer immunotherapy.

Oncogene. 2014 Nov 20; 33(47):5405-14.

5- Rocha C, Papon L, Cacheux W, Marques Sousa P, Lascano V, Tort O, Giordano T, Vacher S, Lemmers B, Mariani P, Meseure D, Medema JP, Bièche I, Hahne M, Janke C.Tubulin glycylases are required for primary cilia, control of cell proliferation and tumor development in colon.

EMBO J. 2014 Oct 1; 33(19):2247-60.

6- Sebti S, Prébois C, Pérez-Gracia E, Bauvy C, Desmots F, Pirot N, Gongora C, Bach AS, Hubberstey AV, Palissot V, Berchem G, Codogno P, Linares LK, Liaudet-Coopman E, Pattingre S BAG6/BAT3 modulates autophagy by affecting EP300/p300 intracellular localization.. Autophagy. 2014 Jul; 10(7):1341-2.

7- Serratrice N, Cubizolle A, Ibanes S, Mestre-Francés N, Bayo-Puxan N, Creyssels S, Gennetier A, Bernex F, Verdier JM, Haskins ME, Couderc G, Malecaze F, Kalatzis V, Kremer EJ. Corrective GUSB transfer to the canine mucopolysaccharidosis VII cornea using a helper-dependent canine adenovirus vector. J Control Release. 2014 May 10; 181:22-31.

8- Pirot N, Delpech H, Deleuze V, Dohet C, Courtade-Saïdi M, Basset-Léobon C, Chalhoub E, Mathieu D, Pinet V. Lung endothelial barrier disruption in Lyl1-deficient mice. Am J Physiol Lung Cell Mol Physiol. 2014 Apr 15; 306(8):L775-85.

9- Cubizolle A, Serratrice N, Skander N, Colle MA, Ibanes S, Gennetier A, Bayo-Puxan N, Mazouni K, Mennechet F, Joussemet B, Cherel Y, Lajat Y, Vite C, Bernex F, Kalatzis V, Haskins ME, Kremer EJ.Corrective GUSB transfer to the canine mucopolysaccharidosis VII brain. Mol Ther. 2014 Apr; 22(4):762-73.

10- Sebti S, Prébois C, Pérez-Gracia E, Bauvy C, Desmots F, Pirot N, Gongora C, Bach AS, Hubberstey AV, Palissot V, Berchem G, Codogno P, Linares LK, Liaudet-Coopman E, Pattingre S. BAT3 modulates p300-dependent acetylation of p53 and autophagy-related protein 7 (ATG7) during autophagy. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4115-20.

11- Ravier MA, Leduc M, Richard J, Linck N, Varrault A, Pirot N, Roussel MM, Bockaert J, Dalle S, Bertrand G. β-Arrestin2 plays a key role in the modulation of the pancreatic beta cell mass in mice.

Diabetologia. 2014 Mar; 57(3):532-41.

12- du Manoir S, Orsetti B, Bras-Gonçalves R, Nguyen TT, Lasorsa L, Boissière F, Massemin B, Colombo PE, Bibeau F, Jacot W, Theillet C. Breast tumor PDXs are genetically plastic and correspond to a subset of aggressive cancers prone to relapse. Mol Oncol. 2014 Mar;8(2):431-43. doi: 10.1016/j.molonc.2013.11.010. Epub 2013 Dec 19. PMID: 24394560

13- Salinas S, Zussy C, Loustalot F, Henaff D, Menendez G, Morton PE, Parsons M, Schiavo G, Kremer EJ. Disruption of the coxsackievirus and adenovirus receptor-homodimeric interaction triggers lipid microdomain- and dynamin-dependent endocytosis and lysosomal targeting. J Biol Chem. 2014 Jan 10; 289(2):680-95.

14- Lopez-Mejia IC1, de Toledo M, Chavey C, Lapasset L, Cavelier P, Lopez-Herrera C, Chebli K, Fort P, Beranger G, Fajas L, Amri EZ, Casas F, Tazi J. Antagonistic functions of LMNA isoforms in energy expenditure and lifespan. EMBO Rep. 2014 May;15(5):529-39.

15- Djouad F, Tejedor G, Toupet K, Maumus M, Bony C, Blangy A, Chuchana P, Jorgensen C, Noël D. Promyelocytic leukemia zinc-finger induction signs mesenchymal stem cell commitment: identification of a key marker for stemness maintenance? Stem Cell Res Ther. 2014 Feb 24;5(1):27.

16- Guérit D, Brondello JM, Chuchana P, Philipot D, Toupet K, Bony C, Jorgensen C, Noël D.FOXO3A regulation by miRNA-29a Controls chondrogenic differentiation of mesenchymal stem cells and cartilage formation. Stem Cells Dev. 2014 Jun 1;23(11):1195-205.

17- Poirier AC, Schmitt P, Rosa RD, Vanhove AS, Kieffer-Jaquinod S, Rubio TP, Charrière GM, Destoumieux-Garzón D.Antimicrobial histones and DNA traps in invertebrate immunity: evidences in Crassostrea gigas. J Biol Chem. 2014 Sep 5;289(36):24821-31.

18- Jemaà M, Morin N, Cavelier P, Cau J, Strub JM, Delsert C.Adult somatic progenitor cells and hematopoiesis in oysters. J Exp Biol. 2014 Sep 1;217(Pt 17):3067-77.

19- Guichet PO1, Guelfi S, Teigell M, Hoppe L, Bakalara N, Bauchet L, Duffau H, Lamszus K, Rothhut B, Hugnot JP.Notch1 stimulation induces a vascularization switch with pericyte-like cell differentiation of glioblastoma stem cells. Stem Cells. 2014 Jun 4. doi: 10.1002/stem.1767.

20- Jérôme Bourien, Yong Tang, Charlène Batrel, Antoine Huet, Marc Lenoir, Sabine Ladrech, Gilles Desmadryl, Régis Nouvian, Jean-Luc Puel, Jing Wang.Contribution of auditory nerve fibers to compound action potential of the auditory nerve. Journal of Neurophysiology Published 1 September 2014 Vol. 112 no. 5, 1025-1039 DOI: 10.1152/jn.00738.2013

21- Mathieu M1, Iampietro M, Chuchana P, Guérit D, Djouad F, Noël D, Jorgensen C. Involvement of angiopoietin-like 4 in matrix remodeling during chondrogenic differentiation of mesenchymal stem cells. J Biol Chem. 2014 Mar 21;289(12):8402-12.

22- Mathieu M1, Vigier S, Labour MN, Jorgensen C, Belamie E, Noël D. Eur Cell Mater.Induction of mesenchymal stem cell differentiation and cartilage formation by cross-linker-free collagen microspheres. 2014 Sep 2;28:82-96; discussion 96-7.

23- Martinez E, Cantet F, Fava L, Norville I, Bonazzi M. Identification of OmpA, a Coxiella burnetii protein involved in host cell invasion, by multi-phenotypic high-content screening. PLoS Pathog. 2014 Mar 20;10(3):e1004013. doi: 10.1371/journal.ppat.1004013. eCollection 2014.

24- Serratrice N, Cubizolle A, Ibanes S, Mestre-Francés N, Bayo-Puxan N, Creyssels S, Gennetier A, Bernex F, Verdier JM, Haskins ME, Couderc G, Malecaze F, Kalatzis V, Kremer EJ Corrective GUSB transfer to the canine mucopolysaccharidosis VII cornea using a helper-dependent canine adenovirus vector.. J Control Release. 2014 May 10;181:22-31. doi: 10.1016/j.jconrel.2014.02.022. Epub 2014 Mar 4.

1- Mazard T, Causse A, Simony J, Leconet W, Vezzio-Vie N, Torro A, Jarlier M, Evrard A, Del Rio M, Assenat E, Martineau P, Ychou M, Robert B, Gongora C. Sorafenib overcomes irinotecan resistance in colorectal cancer by inhibiting the ABCG2 drug-efflux pump. Mol Cancer Ther. 2013 Oct; 12(10):2121-34.

2- Fritz V, Benfodda Z, Henriquet C, Hure S, Cristol JP, Michel F, Carbonneau MA, Casas F, Fajas L. Metabolic intervention on lipid synthesis converging pathways abrogates prostate cancer growth. Oncogene. 2013 Oct 17; 32(42):5101-10.

3- Maumus M, Manferdini C, Toupet K, Peyrafitte JA, Ferreira R, Facchini A, Gabusi E, Bourin P, Jorgensen C, Lisignoli G, Noël D. Adipose mesenchymal stem cells protect chondrocytes from degeneration associated with osteoarthritis. Stem Cell Res. 2013 Sep; 11(2):834-44.

4- Fernandez L, Salinas GF, Rocha C, Carvalho-Pinto CE, Yeremenko N, Papon L, Medema JP, Combe B, Morel J, Baeten D, Hahne M. The TNF family member APRIL dampens collagen-induced arthritis. Ann Rheum Dis. 2013 Aug; 72(8):1367-74.

5- Toupet K, Maumus M, Peyrafitte JA, Bourin P, van Lent PL, Ferreira R, Orsetti B, Pirot N, Casteilla L, Jorgensen C, Noël D. Long-term detection of human adipose derived mesenchymal stem cells after intra-articular injection. Arthritis Rheum. 2013 Jul; 65(7):1786-94.

6- Guérit D, Philipot D, Chuchana P, Toupet K, Brondello JM, Mathieu M, Jorgensen C, Noël D.Sox9-regulated miRNA-574-3p inhibits chondrogenic differentiation of mesenchymal stem cells.

PLoS One. 2013 Apr 23; 8(4):e62582.

7- Hapkova I, Skarda J, Rouleau C, Thys A, Notarnicola C, Janikova M, Bernex F, Rypka M, Vanderwinden JM, Faure S, Vesely J, de Santa Barbara P.High expression of the RNA-binding protein RBPMS2 in gastrointestinal stromal tumors. Exp Mol Pathol. 2013 Apr; 94(2):314-21.

8- Simonin Y, Vegna S, Akkari L, Grégoire D, Antoine E, Piette J, Floc'h N, Lassus P, Yu GY, Rosenberg AR, Karin M, Durantel D, Hibner U.Lymphotoxin signaling is initiated by the viral polymerase in HCV-linked tumorigenesis. PLoS Pathog. 2013 Mar; 9(3):e1003234.

9- Philibert P, Boizet-Bonhoure B, Bashamboo A, Paris F, Aritake K, Urade Y, Leger J, Sultan C, Poulat F.Unilateral cryptorchidism in mice mutant for ptgds. Hum Mutat. 2013 Feb; 34(2):278-82.

10- Ramirez JM1, Bai Q, Péquignot M, Becker F, Kassambara A, Bouin A, Kalatzis V, Dijon-Grinand M, De Vos J. Side scatter intensity is highly heterogeneous in undifferentiated pluripotent stem cells and predicts clonogenic self-renewal. Stem Cells Dev. 2013 Jun 15;22(12):1851-60.

11- Capone SH, Dufresne M, Rechel M, Fleury MJ, Salsac AV, Paullier P, Daujat-Chavanieu M, Legallais C. Impact of alginate composition: from bead mechanical properties to encapsulated HepG2/C3A cell activities for in vivo implantation. PLoS One. 2013 Apr 25;8(4):e62032. doi: 10.1371/journal.pone.0062032. Print 2013.

12- Guichet PO, Bieche I, Teigell M, Serguera C, Rothhut B, Rigau V, Scamps F, Ripoll C, Vacher S, Taviaux S, Chevassus H, Duffau H, Mallet J, Susini A, Joubert D, Bauchet L, Hugnot JP.Cell death and neuronal differentiation of glioblastoma stem-like cells induced by neurogenic transcription factors. Glia. 2013 Feb;61(2):225-39.

13- Manes G, Meunier I, Avila-Fernandez A, Sandro Banfi S, Le Meur G, Zanlonghi X, Corton M, Simonelli F, Brabet P, Labesse G, Audo I, Mohand-Said S, Zeitz C, Sahel J.A, Weber M, Dollfus H, Dhaenens C.M, Allorge D, De Baere E, Koenekoop R.K, Kohl S. CremersJoe G. Hollyfield F. P.M, Senechal A, Hebrar M. Mutations in IMPG1 Cause Vitelliform Macular Dystrophies. The American Journal of Human Genetics 93, 1–8, September 5, 2013

14- Hamze M1, Desmetz C, Berthe ML, Roger P, Boulle N, Brancherau P, Picard E, Guzman C, Tolza C, Guglielmi P.Characterization of resident B cells of vascular walls in human atherosclerotic patients. J Immunol. 2013 Sep 15;191(6):3006-16. doi: 10.4049/jimmunol.1202870. Epub 2013 Aug 16.

15- Le Bouteiller M, Souilhol C, Beck-Cormier S, Stedman A, Burlen-Defranoux O, Vandormael-Pournin S, Bernex F, Cumano A, Cohen-Tannoudji M Notchless-dependent ribosome synthesis is required for the maintenance of adult hematopoietic stem cells..J Exp Med. 2013 Oct 21;210(11):2351-69. doi: 10.1084/jem.20122019. Epub 2013 Sep 23.

16- Campagne C, Reyes-Gomez E, Battistella M, Bernex F, Château-Joubert S, Huet H, Beermann F, Aubin-Houzelstein G, Egidy G. Histopathological atlas and proposed classification for melanocytic lesions in Tyr::NRas(Q61K) ; Cdkn2a(-/-) transgenic mice. Pigment Cell Melanoma Res. 2013 Sep;26(5):735-42. doi: 10.1111/pcmr.12115. Epub 2013 May 30. No abstract available.

17- Hapkova I, Skarda J, Rouleau C, Thys A, Notarnicola C, Janikova M, Bernex F, Rypka M, Vanderwinden JM, Faure S, Vesely J, de Santa Barbara P. High expression of the RNA-binding protein RBPMS2 in gastrointestinal stromal tumors. Exp Mol Pathol. 2013 Apr;94(2):314-21. doi: 10.1016/j.yexmp.2012.12.004. Epub 2013 Jan 4.

1- Sarzi E, Angebault C, Seveno M, Gueguen N, Chaix B, Bielicki G, Boddaert N, Mausset-Bonnefont AL, Cazevieille C, Rigau V, Renou JP, Wang J, Delettre C, Brabet P, Puel JL, Hamel CP, Reynier P, Lenaers G. The human OPA1delTTAG mutation induces premature age-related systemic neurodegeneration in mouse. Brain. 2012 Dec; 135(Pt 12):3599-613.

2- Lascano V, Zabalegui LF, Cameron K, Guadagnoli M, Jansen M, Burggraaf M, Versloot M, Rodermond H, van der Loos C, Carvalho-Pinto CE, Kalthoff H, Medema JP, Hahne M.

The TNF family member APRIL promotes colorectal tumorigenesis. Cell Death Differ. 2012 Nov; 19(11):1826-35.

3- Akkari L*, Grégoire D*, Floc'h N, Moreau M, Hernandez C, Simonin Y, Rosenberg AR, Lassus P, Hibner U. Hepatitis C viral protein NS5A induces EMT and participates in oncogenic transformation of primary hepatocyte precursors. J Hepatol. 2012 Nov; 57(5):1021-8.

4- Blanchet E, Annicotte JS, Pradelli LA, Hugon G, Matecki S, Mornet D, Rivier F, Fajas L. E2F transcription factor-1 deficiency reduces pathophysiology in the mouse model of Duchenne muscular dystrophy through increased muscle oxidative metabolism. Hum Mol Genet. 2012 Sep 1; 21(17):3910-7.

5- Lutzmann M, Grey C, Traver S, Ganier O, Maya-Mendoza A, Ranisavljevic N, Bernex F, Nishiyama A, Montel N, Gavois E, Forichon L, de Massy B, Méchali M. MCM8- and MCM9-Deficient Mice Reveal Gametogenesis Defects and Genome Instability Due to Impaired Homologous Recombination. Mol Cell. 2012 Aug 24; 47(4):523-34.

6- Duclot F, Lapierre M, Fritsch S, White R, Parker MG, Maurice T, Cavaillès V. Cognitive impairments in adult mice with constitutive inactivation of RIP140 gene expression. Genes Brain Behav. 2012 Feb; 11(1):69-78.

7- Sirvent A, Benistant C, Roche S. Oncogenic signaling by tyrosine kinases of the SRC family in advanced colorectal cancer.

Am J Cancer Res. 2012; 2(4):357-71.

8- Nassour M, Idoux-Gillet Y, Selmi A, Côme C, Faraldo ML, Deugnier MA, Savagner P. Slug controls stem/progenitor cell growth dynamics during mammary gland morphogenesis. PLoS One. 2012; 7(12):e53498.

9- Chekroud K, Guillou L, Grégoire S, Ducharme G, Brun E, Cazevieille C, Bretillon L, Hamel CP, Brabet P, Pequignot MO.Fatp1 Deficiency Affects Retinal Light Response and Dark Adaptation, and Induces Age-Related Alterations. PLoS One. 2012; 7(11):e50231.

10- Fritz, V., Benfodda, Z., Henriquet, C., Hure, S., Cristol, J. P., Michel, F., Carbonneau, M. A., Casas, F. and Fajas, L.Metabolic intervention on lipid synthesis converging pathways abrogates prostate cancer growth. Oncogene. 2012: 1-10.

11- The TNF family member APRIL promotes colorectal tumorigenesis. Lascano, V., Fernandez, L., Cameron, K., Guadagnoli, M., Jansen, M., Burggraaf, M., Versloot, M., Rodermond, H., van der Loos, C., Carvalho-Pinto, C. E., Medema, J. P., and Hahne, M. Cell Death Differ 2012; 19, 1826-1835.

12- Guichet PO, Bieche I, Teigell M, Serguera C, Rothhut B, Rigau V, Scamps F, Ripoll C, Vacher S, Taviaux S, Chevassus H, Duffau H, Mallet J, Susini A, Joubert D, Bauchet L, Hugnot JP. Cell death and neuronal differentiation of glioblastoma stem-like cells induced by neurogenic transcription factors. Glia. 2013 Feb; 61(2):225-39. doi: 10.1002/glia.22429. Epub 2012 Oct 9.

13- Travo C, Gaboyard-Niay S, Chabbert C. Plasticity of Scarpa's Ganglion Neurons as a Possible Basis for Functional Restoration within Vestibular Endorgans. Front Neurol. 2012 Jun 6; 3:91. doi: 10.3389/fneur.2012.00091. eCollection 2012.

14- KLucas O, Hilaire C, Delpire E, Scamps F.CC3-dependent chloride extrusion in adult sensory neurons. Mol Cell Neurosci. 2012 Jul;50(3-4):211-20. doi: 10.1016/j.mcn.2012.05.005. Epub 2012 May 18

15- Ho-Pun-Cheung A1, Bazin H, Gaborit N, Larbouret C, Garnero P, Assenat E, Castan F, Bascoul-Mollevi C, Ramos J, Ychou M, Pèlegrin A, Mathis G, Lopez-Crapez E. Quantification of HER expression and dimerization in patients' tumor samples using time-resolved Förster resonance energy transfer. PLoS One. 2012;7(7):e37065. doi: 10.1371/journal.pone.0037065. Epub 2012 Jul 19.

16- Paul C, Sardet C, Fabbrizio E. The histone- and PRMT5-associated protein COPR5 is required for myogenic differentiation. Cell Death Differ. 2012 May;19(5):900-8.

17- Sirvent A, Vigy O, Orsetti B, Urbach S, Roche S. Analysis of SRC oncogenic signaling in colorectal cancer by stable isotope labeling with heavy amino acids in mouse xenografts. Mol Cell Proteomics. 2012 Dec;11(12):1937-50.

18- Léguillier T, Vandormael-Pournin S, Artus J, Houlard M, Picard C, Bernex F, Robine S, Cohen-Tannoudji M. Omcg1 is critically required for mitosis in rapidly dividing mouse intestinal progenitors and embryonic stem cells. Biol Open. 2012 Jul 15;1(7):648-57. doi: 10.1242/bio.20121248. Epub 2012 May 23.

19- Campagne C, Julé S, Bernex F, Estrada M, Aubin-Houzelstein G, Panthier JJ, Egidy G. RACK1, a clue to the diagnosis of cutaneous melanomas in horses. BMC Vet Res. 2012 Jun 29;8:95. doi: 10.1186/1746-6148-8-95.

20- Djian-Zaouche J, Campagne C, Reyes-Gomez E, Gadin-Czerw S, Bernex F, Louise A, Relaix F, Buckingham M, Panthier JJ, Aubin-Houzelstein G. Pax3( GFP ) , a new reporter for the melanocyte lineage, highlights novel aspects of PAX3 expression in the skin. Pigment Cell Melanoma Res. 2012 Sep;25(5):545-54. doi: 10.1111/j.1755-148X.2012.01024.x. Epub 2012 Jul 12.

1- Mamaeva D, Ripoll C, Bony C, Teigell M, Rothhut B, Bieche I, Lidereau R, Privat A, Rigau V, Guillon H, Noel D, Bauchet L, Hugnot JP. Isolation of mineralizing Nestin+ Nkx6.1+ vascular muscular cells from the adult human spinal cord. BMC Neurosci. 2011 Oct 10; 12:99.

2- Blanchet E, Annicotte JS, Lagarrigue S, Aguilar V, Clapé C, Chavey C, Fritz V, Casas F, Apparailly F, Auwerx J, Fajas L. E2F transcription factor-1 regulates oxidative metabolism. Nat Cell Biol. 2011 Aug 14;13(9):1146-52.

3- Hatchi E, Rodier G, Lacroix M, Caramel J, Kirsh O, Jacquet C, Schrepfer E, Lagarrigue S, Linares LK, Lledo G, Tondeur S, Dubus P, Sardet C, Le Cam L. E4F1 deficiency results in oxidative stress–mediated cell death of leukemic cells. J Exp Med. 2011 Jul 4; 208(7):1403-17.

4- Rosa RD, Santini A, Fievet J, Bulet P, Destoumieux-Garzon D, Bachere E. Big defensins, a diverse family of antimicrobial peptides that follows different patterns of expression in hemocytes of the oyster Crassostrea gigas. PLoS One. 2011;6(9):e25594.

5- Courties G, Baron M, Presumey J, Escriou V, van Lent P, Scherman D, Cantagrel A, van den Berg WB, Jorgensen C, Apparailly F, Davignon JL. Cytosolic phospholipase A2α gene silencing in the myeloid lineage alters development of Th1 responses and reduces disease severity in collagen-induced arthritis. Arthritis Rheum. 2011 Mar;63(3):681-90.

6- Pieraut S, Lucas O, Sangari S, Sar C, Boudes M, Bouffi C, Noel D, Scamps F. An autocrine neuronal interleukin-6 loop mediates chloride accumulation and NKCC1 phosphorylation in axotomized sensory neurons. J Neurosci. 2011 Sep 21; 31(38):13516-26.

1- Lacroix M, Caramel J, Goguet-Rubio P, Linares LK, Estrach S, Hatchi E, Rodier G, Lledo G, de Bettignies C, Thépot A, Deraison C, Chébli K, Hovnanian A, Hainaut P, Dubus P, Sardet C, Le Cam L. Transcription factor E4F1 is essential for epidermal stem cell maintenance and skin homeostasis. Proc Natl Acad Sci U S A. 2010 Dec 7; 107(49):21076-81.

2- Pirot N, Deleuze V, El-Hajj R, Dohet C, Sablitzky F, Couttet P, Mathieu D, Pinet V. LYL1 activity is required for the maturation of newly formed blood vessels in adulthood. Blood. 2010 Jun 24; 115(25):5270-9.

3- Glondu-Lassis M, Dromard M, Lacroix-Triki M, Nirdé P, Puech C, Knani D, Chalbos D, Freiss G. PTPL1/PTPN13 Regulates Breast Cancer Cell Aggressiveness through Direct Inactivation of Src Kinase. Cancer Res. 2010 Jun 15; 70(12):5116-26.

4- Charbonnier LM, Han WG, Quentin J, Huizinga TW, Zwerina J, Toes RE, Jorgensen C, Louis-Plence P. Adoptive transfer of IL-10-secreting CD4+CD49b+ regulatory T cells suppresses ongoing arthritis. J Autoimmun. 2010 Jun; 34(4):390-9.

5- Gabriel Courties, Virginia Seiffart, Jessy Presumey, Virginie Escriou, Daniel Scherman, Jochen Zwerina, Gisela Ruiz, Natalia Zietara, Jadwiga Jablonska, Siegfried Weiss, Andrea Hoffmann, Christian Jorgensen, Florence Apparailly, and Gerhard Gross. In vivo RNAi-mediated silencing of TAK1 decreases inflammatory Th1 and Th17 cells through targeting of myeloid cells. July 17, 2010 Blood November 4, 2010 vol. 116 no. 18 3505-3516.

6- Beaulieu E, Ngo D, Santos L, Yang YH, Smith M, Jorgensen C, Escriou V, Scherman D, Courties G, Apparailly F, Morand EF. Glucocorticoid-induced leucine zipper is an endogenous antiinflammatory mediator in arthritis. Arthritis Rheum. 2010 Sep; 62(9):2651-61. doi: 10.1002/art.27566.

7- Khoury M, Courties G, Fabre S, Bouffi C, Seemayer CA, Vervoordeldonk MJ, Tak PP, Jorgensen C, Apparailly F.Adeno-associated virus type 5-mediated intraarticular administration of tumor necrosis factor small interfering RNA improves collagen-induced arthritis. Arthritis Rheum. 2010 Mar; 62(3):765-70. doi: 10.1002/art.27302.

1- Sabourin JC, Ackema KB, Ohayon D, Guichet PO, Perrin FE, Garces A, Ripoll C, Charité J, Simonneau L, Kettenmann H, Zine A, Privat A, Valmier J, Pattyn A, Hugnot JP. A mesenchymal-like ZEB1(+) niche harbors dorsal radial glial fibrillary acidic protein-positive stem cells in the spinal cord. Stem Cells. 2009 Nov; 27(11):2722-33.

2- Annicotte JS, Blanchet E, Chavey C, Iankova I, Costes S, Assou S, Teyssier J, Dalle S, Sardet C, Fajas L. The CDK4-pRB-E2F1 pathway controls insulin secretion. Nat Cell Biol. 2009 Aug;11(8):1017-23.

3- Maurice T, Hippert C, Serratrice N, Dubois G, Jacquet C, Antignac C, Kremer EJ, Kalatzis V. Cystine accumulation in the CNS results in severe age-related memory deficits. Neurobiol Aging. 2009 Jun; 30(6):987-1000.

4- L-M. Charbonnier, W.G.H. Han, J. Quentin, T.W.J. Huizinga, J.Zwerina, R.Toes, C. Jorgensen, P. Louis-Plence. Adoptive transfer of IL-10-secreting CD4+CD49b+ regulatory T cells suppresses ongoing arthritis. J Autoimmun. 2009 Oct 30

 

Remise de prix Nelly Pirot
Remise de prix Nelly Pirot

Aller au haut